Get answers to frequently asked questions about Osphena® (ospemifene)

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How can I save on my Osphena prescription?
Please click here to visit our savings section for details.
Do I need to activate an Osphena Savings Card before the first use?
No, you don’t need to activate an Osphena Savings Card before you use it.
Must I wait a specific number of days between prescription refills to use the savings offer?
The Osphena Savings Program does not require that you wait a specific number of days between Osphena prescription refills. However, your individual insurer may have limitations on how quickly they will approve your monthly refill. Always check with your insurer first for details.
Can patients use the Osphena Savings Program for mail-order purchases?
Yes, the Osphena Savings Program may be used with mail-order purchases with a valid prescription. To redeem the offer, give your mail-order pharmacy the Osphena Savings Program information.
What if I misplace or damage my Osphena Savings Card?
If you misplace or damage your Osphena Savings Card you can download a new one. Your pharmacy may also keep a record of your Osphena Savings Card on file.
Can I use more than one Osphena Savings Card at the same time?
No, you can only use one Osphena Savings Card at a time. Your Osphena Savings Card is eligible for several uses. You don't need to use a different card each time. Your pharmacy may also keep your information on file so you don't have to show it each time.
Can I use the Osphena Savings Program if I have not met my deductible?
Yes. And the out-of-pocket expense can be applied to your deductible.
If I received an Osphena Savings Card, do I still need a prescription?
Yes. The Osphena Savings Program is for use ONLY with a valid Osphena prescription.
Is the Osphena Savings Program accepted at all pharmacies?
The Osphena Savings Program is accepted at most retail pharmacies in the United States and Puerto Rico. If a pharmacy decides not to accept the offer, you may receive savings through a rebate check after you have purchased your Osphena prescription. Call the number on the back of the Osphena Savings Card for information on how to submit for your reimbursement.
Do I need to show the Osphena Savings Card to the pharmacist each time I need a refill?
Although some pharmacies may keep your Osphena Savings Card information on file, it’s best to always bring your Osphena Savings Card to the pharmacy with your valid Osphena prescription or refill request.
Is there a patient assistance program for patients who cannot afford Osphena?
Duchesnay USA does not offer a patient assistance program at this time.
If I previously used a savings offer, am I eligible to use the new savings offer?
Yes. Even if you have previously used an Osphena Savings Card, you may present a valid prescription at the pharmacy with your new savings card and you will be eligible for the new offer.

Important Safety Information and Indication

Osphena works like estrogen in the lining of the uterus, but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause, so tell him or her right away if this happens while you are using Osphena.

Osphena may increase your chances of having a stroke or blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Call your healthcare provider right away if you have changes in vision or speech, sudden new severe headaches, and severe pains in your chest or legs with or without shortness of breath, weakness and fatigue. Osphena should not be used if you have unusual vaginal bleeding, have or have had certain types of cancers (including cancer of the breast or uterus), have or have had blood clots, have had a stroke or heart attack, have severe liver problems, are allergic to Osphena or any of its ingredients, or think you may be pregnant. Tell your healthcare provider if you are going to have surgery or will be on bed rest.

Possible side effects of Osphena

Serious but less common side effects can include stroke, blood clots and cancer of the lining of the uterus.

Common side effects may include hot flashes, vaginal discharge, muscle spasms and increased sweating.

Tell your healthcare provider about all of the medicines and supplements you take, as some medicines may affect how Osphena works. Osphena may also affect how other medicines work.

Duchesnay USA encourages you to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Indication : What is Osphena® (ospemifene)?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse, a symptom of changes in and around your vagina, due to menopause.

Please read accompanying Patient Information for Osphena® (ospemifene) tablets, including Boxed WARNING in the U.S. Full Prescribing Information.